Molds and Genes

Sun May 11 09:41:41 -0700 2008
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Molds have the ability to detect foreign DNA and to turn the genes off, so that these abnormalities aren't passed on with reproduction. Being able to precisely pick and choose which genes are expressed or not this way could lead to novel approaches in treating diseases.

.."“Meiotic silencing also occurs in worms, mice and human beings,” said Patrick Shiu, assistant professor of biological sciences in the MU College of Arts and Science. “It’s unlikely that all share the same mechanism, but the principle of targeting unpaired DNA for silencing seems to be found in both simple and complex organisms. Knowing the process of how DNA in molds is targeted for silencing could be important for silencing genes you don’t want to be expressed, like disease-causing genes.”"